Pharmacological immunosuppressive agents.

نویسنده

  • J. R. Salaman
چکیده

A vast range of different compounds seem capable of depressing the immune response, however, it has been disappointing that so few of these have shown potential as immunosuppressive agents in man. The action of many has been to suppress lymphocyte reactivity in vitro and of those that are capable of prolonging graft survival in animals in addition, just a handful have been found to be safe and effective in man. It is not intended in this paper to discuss in great detail the properties of most of these compounds since many excellent reviews already exist,-5 rather I would wish to concentrate on those drugs that have proved useful as immunosuppressive agents in man.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

BEST PRACTICE Current concepts for the management of systemic lupus erythematosus in adults: a therapeutic challenge

Systemic lupus erythematosus (SLE) is a chronic, autoimmune rheumatic disease with many clinical presentations typically affecting women of childbearing age. The successful therapy of SLE depends upon treating both symptoms and the underlying inflammation. Both non-pharmacological as well as pharmacological therapies are invariably required. Non-pharmacological therapy includes avoiding over-ex...

متن کامل

Current concepts for the management of systemic lupus erythematosus in adults: a therapeutic challenge.

Systemic lupus erythematosus (SLE) is a chronic, autoimmune rheumatic disease with many clinical presentations typically affecting women of childbearing age. The successful therapy of SLE depends upon treating both symptoms and the underlying inflammation. Both non-pharmacological as well as pharmacological therapies are invariably required. Non-pharmacological therapy includes avoiding over-ex...

متن کامل

Immunomodulating Drugs

Immunopharmacology is the study of the use of pharmacological agents as modulators of immune responses. The principal applications are in the use of immunosuppressive agents (i.e., compounds that suppress undesirable immune responses) and immunostimulating agents (i.e., drugs, microorganisms, or biological products that enhance or augment immune responses). Three major indications for immunothe...

متن کامل

Clinical and Experimental Immunology

In the past 40 years, prognosis for patients with systemic lupus erythematosus (SLE) has improved, with 10-year survival now approximately 90%. This is due probably to a combination of earlier disease diagnosis and diagnosis of milder disease, due in part to availability of multiple serological tests for SLE, use of steroids and other immunosuppressive agents, and availability of renal dialysis...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Ulster Medical Journal

دوره 50  شماره 

صفحات  -

تاریخ انتشار 1981